alt Hacker NewsDoes creatine make you smarter?
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I have severe sleep apnea as well as insomnia. I may also be a multi-phasic sleeper. In any case my average sleep per night is ~3.5 hours with only ~1.5 hours of deep sleep. I use light therapy, CPAP, medications, etc but none of it solves my problems. I started taking creatine daily a couple of months ago. I've noticed a significant uptick in my cognitive abilities, despite being constantly sleep deprived. TFA doesn't touch on this apparent benefit of creatine, so thought I'd mention it for others who might be suffering from similar sleep issues.
I take 5g/day, through better part of last 9-12 months (don't remember when I started).
No noticeable cognitive difference/improvement. And the more I've researched creatine the less convinced I am that there are reliable conclusions about cognitive impacts.
Significant physical changes! But other than the pure aesthetics, it's hard to say that my strength increases are tied to creatine or instead a solid routine, plan, diet, and progressive overload. Probably some all of above.
I also take whey protein isolate (20-25g at least once a day)
The Nootropic space fascinates me. A few observations:
- Not sure if caffeine is considered nootropic. Caffeine definitely makes a difference.
- Unclear if placebo effect or real, L-theanine seems to help with calm and focus.
- Otherwise, when it comes to what I'm sure alters my state/body/etc. - drugs! And I'm not suggesting anything specific but my point is the effects are obvious/real/etc. vs. much of the supplement space that suffers from very murky conclusions (imo).
Sometimes I stay up until 1–3 a.m. because I'm working on a problem that's so interesting I can't stop until I make progress.
If I know I'm only going to get a few hours of sleep, I'll take 5–10 g of creatine, drink plenty of water, and go to bed. The next morning, I usually don't wake up with a headache.
If I skip the creatine under the same conditions, I'm much more likely to wake up with a headache after a short night's sleep.
Now it's become a habit, I automatically take creatine whenever I know my sleep duration is going to be much shorter than usual.
Most people taking creatine just need to drink water. They drink more water using creatine. In reality, the water/hydration is doing the heaviest lift, not the creatine.
I wonder if there’s any long term studies like how the body gets adjusted to creatine. Because human body is remarkable at adjusting and setting new baselines and I wonder if it’s true with creatine as well, like to have the same effect you need to take more creatine the longer you keep on taking it
A different discussion on the same general topic 51 days ago (and now flagged)
>Contrary to the common myth, thinking hard does not burn significantly more calories. (Demonstration: Start thinking hard, and watch as your heart rate does not increase.)
this is wrong [0] , it's just hard to measure.
This matches what Gwern wrote years ago [0]. It does unequivocally make you stronger though. So if you're training anyway, may as well take it and hope it makes you smarter as well (just believing might be enough for that sweet placebo effect).
This made me wonder if sun exposure/vitamin D has any impact on storing or processing creatine, and maybe that's why the results in Australia were so much greater
I have definitely noticed improvements taking a larger dose with my energy when low on sleep, check out McMorris et al. (2006) which is not cited here. I agree it probably doesn't make you generally more 'smart' but it does may improve function under stress, e.g. when sleep deprived, also see Gordji-Nejad et al. (2024). I think the sleep benefits should at least be mentioned in this article.
Also search for 'sleep' in this comment section, seems many see similar improvements!
> Wikipedia quotes a paper saying people make / recycle around 50 kilograms per day. That would imply that people make around 0.5787 grams per second. But this is in tension with the idea that people use 100 watts at rest. Since that 100 watt number seems to be more strongly established, I think 1 gram per second is a better estimate.
The cited paper in Wikipedia might be accurate and the author is just expecting "at rest" to mean awake but mostly idle. I'd wager that during sleep, we use less than 100W. For the sake of argument if you take out 8 hours (asleep time) from a 24 hour period, you end up with a rate of ~0.8681 grams per second, much closer to 1g/s. Anyway, just a little fun with numbers.
In my experience, it wont make you smarter but my brain just feels more energized to think.
> Available short and long-term studies in healthy and diseased populations, from > infants to the elderly, at dosages ranging from 0.3 to 0.8 g/kg/day for up to 5 > years have consistently shown that creatine supplementation poses no adverse > health risks and may provide a number of health and performance benefits.
They missed a zero behind the comma, didn't they?
Studies I read seems to show a marginal boost in cognitionl and memory, but only if you were otherwise overtaxed for some reason.
Like being tired, stressed, etc...
Personally I have noticed a lot less cognitive impairment after a poor night’s sleep since starting on 10g per day. It seems to make a noticeable difference in my ability to reason and to act having slept less than 7 hours per night, even on consecutive nights.
Dang, missed opportunity to explain the actin-myosine sliding filament theory.
> Maybe for some reason, Rae et al.’s cohort had lower baseline creatine levels?
Well, yes. It is well known that you must eat fish, beef, i.e., animal protein, to get close to optimal levels of creatine.
I started taking 5g for cognition. Never any clear signal for that, but it does seem to help a bit with my (more than occasional) sleep deprivation. Mostly with fighting off headaches.
> This in turn may increase the long-term gainz from strength-training exercise
Why is "gains" spelled this way? I found myself suddenly trusting the whole thing a little less. But maybe I'm missing something. Is this jargon in the body building world or something? Author being cheeky?
> thinking hard does not burn significantly more calories
Up to 50 Cal extra over ~2 hours of intense thinking IS significant given brains consume 240-400 Cal over 24 hours.
> Start thinking hard, and watch as your heart rate does not increase.
And yet you soon get tired and slow down. Now try the opposite. Stretch or punch the air a few times to get the heart rate going. You'll sustain brain performance for longer. Try it.
Perhaps the problem is that higher brain activity SHOULD trigger heart rate increase, but doesn't due to one of many design defects of the human body.
Okay, I skimmed the article.
Is creatine safe to supplement for children?
Its something you might aswell just take, no proven side negative side effects, unless you are gulping it, it will benefit you
I experienced dramatic and obvious hair loss in my late twenties after starting creatine supplementation. I'm talking hundreds of hairs coming out every shower. It stopped when I stopped creatine. No I didn't make any other changes in diet or lifestyle at the time. I hadn't even heard of the link before that. This is actually one of those things that made me start doubting "the science" in general because it's supposedly not true, but, it obviously is true for my head beyond a reasonable doubt.
I think another source of variation on the results is the actual nutritional intake of the subjects.
The vegan/vegetarian is a big spectrum. A vegetarian eating plenty of dairy products and eggs should in theory be much better creatine-equipped than a poor vegan student feeding on noodles and ketchup pastas. A lot of pseudo-meat for vegans are full of processed shit.
Confusion will be even higher if you include fish in the vegetarian diet, which is odd but some people do that.
Could the cognitive effect works in the case of creatine deficiency (vegan) and not in the case a vegetarian (low creatine but not deficient) ?
I just ordered some yesterday because I saw something that reminded what my friend said recently about it boosting cognition. Then this morning I saw it mentioned in some health segment on tv. Now I stumble upon this discussion. Hmmm.
I remember learning about Creatine as a weightlifting teen
I never ended up doing it because you had to cycle it, and it was just one more thing to track
Is it the same case in 2026? Is there a simple pill I can take?
if you are using to slim down it will hold on to water unless you are bulking i dont see creatine to be consumed regularly
if you truly want fuel for the brain nothing beats keto
Saved you a click:
> Does creatine make you smarter?
> I don’t know. Maybe a little.
The conclusions aren't any different (it's one of the few thing that helps strength, poses no danger to your hair, and almost certainly does nothing for cognition), but the articles at https://www.strongerbyscience.com/?s=creatine are far more comprehensive, including the famous extremely long podcast episodes they used to do.
The one thing this misses is many supplements are tainted, which skews the popular perception of both upsides and risks. This was especially true in the US prior to 2005 or so when prohormones were still legal over the counter. Anything branded that wasn't just pure creatine was extremely likely to actually be a low-dose oral steroid, which really can make you lose hair and will increase strength quite a bit more than any dietary supplement.
This also misses caffeine as the other a-tier supplement that consistently shows strength increases in RCTs, though of course, caffeine is more frought than creatine because you build tolerance and it can disturb sleep.
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Article's answer to its own question:
It safely builds muscle and boosts cognition.
I don’t think they’re strong evidence that it does anything beyond helping you build muscle. There are some people say they think clearer, but I don’t think that’s been measured in any significant way.
Given LLM's is being smarter still a worthwhile to optimize with supplements?
Good discussion, but this conclusion:
> I don’t know. Maybe a little.
is not the right way to interpret the null result (insufficient evidence to reject null hypothesis that it has no effect) because the prior for supplements that people are trying to sell you is so low. In the absence of clear, strong evidence, you should assume the the whole thing is just an example of motivated reasoning. People want nootropics to be real, and other people really want to sell you readily available powders by claiming they have nootropic properties. In that environment, they were always going to trying to concoct a similar narrative about some supplement, and it just happened to be creatine. Those efforts were always going to result in a handful of "positive" studies that turn out to be non-reproducible, maybe because of p-hacking, maybe because of publication bias, maybe because of outright fraud. This is what the literature always looks like for stuff that just doesn't work. If it did work - if the effect size was large enough that you could personally detect it in your own life - then the papers would be trying to put error bars around the effect size, not trying (and failing) to barely distinguish it from a placebo.
“If your experiment needs statistics, you ought to have done a better experiment.” - Ernest Rutherford