I use air purifiers mounted on my windows, running continuously except in the deep summer and deep winter. This makes my air contain 50-100x fewer particulates than the outdoor air. In contrast, the best I can achieve with floor air purifiers as people have them is a 5-10x reduction. The window purifiers also keep excess CO2 and VOCs out.
Health improvements are not measurable any more if you go below 5 mcg/m2 average level of PM2.5 particulates. For 50x reduction to be beneficial, you need to live in an area where the pollution is 250 mcg/m2, which is an extreme level found only in a few unfortunate places on Earth. 5-10x reduction is reasonable almost everywhere.
You have activated carbon to filter out the VOCs?
> The window purifiers also keep excess CO2 and VOCs out.
I assume you mean that the increased air-exchange (purified or not) helps CO2 that originates inside the house to leave promptly? (Equalizing it with the outdoors.)
Literally "keeping CO2 out" is a much trickier and more-expensive proposition.