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profsummergigyesterday at 10:38 PM5 repliesview on HN

So many misconceptions in this writeup.

Here's one: even if it were genetic, there could be triggering environmental factors that trigger the onset of autism (I'm just giving a hypothetical example, not making a claim here).


Replies

nomeltoday at 12:44 AM

For example, 45% reduction in symptoms from fecal transplant: https://news.ycombinator.com/item?id=48158494

> Prior to the study, 83% of participants had "severe" autism. Two years later, only 17% were rated as severe, 39% as mild or moderate, and incredibly, 44% were below the cut-off for mild ASD.

Incredible! Sure, there could be a genetic component to what flourishes, or ever seeded, in one's microflora, but there's definitely some external complexities involved here.

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strideashorttoday at 6:06 AM

Not onset, that makes no sense.

Environment makes certain traits visible - eg noise and smell sensory issues, even social settings. Put me in a forest and i will be indistinguishable from a neuro-prevalent - no social pressure, no noise, no smells. Actually the neuro-prevalent might be suffering for the lack of those i suppose

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dwrobertstoday at 6:52 AM

The writeup is a summary of having done a meta analysis of actual research. It also covers environmental factors already

bluGillyesterday at 10:42 PM

They specifically said there are environmental factors, and not all of them are known. A few are known though: older parents for example.

sksisnbsyesterday at 11:06 PM

Wouldn’t susceptibility to those environmental factors be dictated by your genetics?